What Are Polynucleotides and How Does Rejuran Work?
Polynucleotides are chains of nucleotides, the building blocks of DNA and RNA. In Rejuran, these are purified DNA fragments extracted from salmon. Before you react to that detail, understand that salmon DNA is remarkably compatible with human skin because it shares similar structural properties and doesn’t trigger immune responses.
When Rejuran is injected into your skin, the polynucleotides act as biological signals. They tell your cells to ramp up repair processes, increase collagen and elastin production, and improve cellular turnover. This isn’t about adding volume or structure like traditional gel-based treatments. It’s about improving your skin’s fundamental health and function.
Rejuran works through multiple mechanisms simultaneously. The polynucleotides stimulate fibroblasts (the cells that produce collagen), reduce inflammation, promote the formation of new blood vessels to improve nutrient delivery, and provide antioxidant protection against environmental damage. Think of it as giving your skin the raw materials and instructions it needs to repair itself more effectively.
Results develop gradually because you’re working with your body’s natural processes rather than creating immediate visible changes. Most people notice improved skin texture and hydration within four to six weeks, with continued improvement over the following months as collagen production increases.
What Skin Concerns Does Rejuran Address?
Rejuran is particularly effective for concerns that stem from cellular damage, hydration loss, or declining collagen production. Because it focuses on improving your skin’s underlying health and function rather than creating immediate cosmetic changes, it addresses issues that other treatments often miss.
Early Signs of Ageing and Fine Lines
Fine lines and early ageing often appear before more obvious wrinkles develop. These subtle changes show up as delicate lines around your eyes, across your forehead, or near your mouth. Rejuran addresses these by stimulating collagen and elastin production from within.
The treatment doesn’t freeze muscles or fill the lines. Instead, it encourages your skin cells to produce more structural proteins naturally. Over time, this helps soften the appearance of fine lines while maintaining natural facial movement and expression.
Skin Texture and Quality Issues
Uneven skin texture, enlarged pores, and general dullness respond well to Rejuran therapy. If your skin feels rough, looks lacklustre, or has lost that smooth, refined quality it once had, cellular regeneration can help. The treatment promotes better cell turnover and improved skin structure at a foundational level.
This is where the “Glass Skin” effect comes in. Glass Skin refers to a complexion that’s so clear, smooth, and luminous it resembles glass. Rejuran supports this by refining pore appearance, improving light reflection across your skin’s surface, and creating a more even, translucent quality.
Hydration and Skin Barrier Health
Dehydrated skin and a compromised skin barrier create a cascade of issues, including sensitivity, dullness, and accelerated ageing. Rejuran helps restore your skin’s natural ability to retain moisture by strengthening the barrier and increasing hyaluronic acid levels.
Under-eye circles, under-eye hollows, and crepey skin around the eyes often result from volume loss combined with thin, dehydrated skin. Rejuran i is specifically formulated for this delicate area. It improves hydration and skin quality in areas too fragile for traditional volumising approaches.
What to Expect: Rejuran Treatment and Results
Rejuran involves a series of sessions designed to build progressive improvements in your skin. Understanding the process, timeline, and recovery helps you plan appropriately and set realistic expectations.
The Treatment Process
Rejuran is performed by our registered nurses using a fine needle technique. The treatment area is cleansed and marked, then the polynucleotide solution is injected into multiple points across your skin using small, precise injections. This creates a microtrauma that triggers your skin’s healing response while delivering the active ingredients.
The session typically takes 20 to 40 minutes, depending on the treatment area. Most people describe the sensation as small pinpricks with mild discomfort. Because the solution is injected with multiple needle punctures, you may see small raised bumps immediately after treatment. These settle within 24 to 48 hours.
For optimal results, we recommend a series of three sessions spaced two to four weeks apart. After completing your initial series, maintenance treatments every six to twelve months help sustain your results and support ongoing skin health.
Results Timeline and What You’ll Notice
Some clients notice improved hydration and skin texture within days of their first Rejuran treatment. However, the full regenerative effects develop gradually over several weeks as your skin produces new collagen and repairs cellular damage.
The most significant improvements typically become apparent after completing your full treatment series. You might notice your skin feels smoother, looks clearer, and has a more luminous quality. Fine lines appear softer, pores look refined, and overall skin tone becomes more even.
Results continue to improve for up to three months after your final session as collagen production peaks. This gradual timeline reflects the treatment’s regenerative nature rather than creating immediate visible changes.
Aftercare and Recovery
Immediately after Rejuran treatment, your skin will show small raised bumps at the injection points. These are normal and expected. Mild redness, swelling, or minor bruising may occur but typically resolve within one to two days. Some people experience temporary flaking, dryness, or peeling over the following few days.
Avoid makeup for the first 24 hours if possible. Skip intense exercise, hot showers, saunas, and swimming pools for 48 hours to prevent excessive heat and bacteria exposure on freshly treated skin. Sun protection is important. Use SPF 50+ daily and avoid direct sun exposure for at least two weeks after each session.
Combining Rejuran with Other Treatments
Rejuran works well as a standalone option, but many clients achieve more comprehensive results by combining it with complementary treatments. The key is sequencing treatments appropriately and understanding how different approaches work together.
Rejuran focuses on cellular regeneration and skin quality. It doesn’t add volume or relax muscles. This makes it an excellent foundation treatment that can be layered with other services addressing different concerns. For example, you might use Rejuran to improve overall skin texture and hydration, then address specific deeper lines or volume loss with targeted treatments.
Skin boosting treatments and Rejuran complement each other beautifully. While Rejuran promotes cellular repair and collagen production through polynucleotides, skin boosters focus primarily on intense hydration through hyaluronic acid. Used together, they address both structural regeneration and moisture retention. Dermapen Skin Needling or Genius RF microneedling can also enhance Rejuran results by creating additional controlled injury that stimulates collagen production through a different mechanism.
For clients dealing with both sun damage and skin quality concerns, combining Rejuran with laser treatments for pigmentation creates a comprehensive approach. The laser addresses existing pigmentation and vascular damage, while Rejuran supports the skin’s healing and regeneration following laser treatment. Timing matters here. We typically recommend spacing laser and Rejuran sessions at least two to four weeks apart to avoid overstimulating your skin.
Who Is a Good Candidate for Rejuran?
Rejuran suits a wide range of people, but it’s particularly valuable for those noticing early signs of ageing or wanting to improve overall skin quality rather than address specific deep lines or volume loss. Living on the Sunshine Coast means your skin faces ongoing challenges from UV exposure, outdoor lifestyle, and coastal climate. Rejuran can help repair and strengthen skin that’s been affected by these environmental factors.
You’re an ideal candidate if you’re seeing dullness, early fine lines, rough texture, or loss of that fresh, hydrated glow you once had. The treatment works well for people in their late twenties to early forties who want to build collagen reserves proactively, as well as more mature clients addressing accumulated sun damage and dehydration. If you’re dealing with under-eye circles, under-eye hollows, or crepey skin around the eyes, the specialised Rejuran i formulation offers a gentle option for this delicate area.
Rejuran isn’t suitable during pregnancy or breastfeeding. Active skin infections, inflammatory conditions, or known allergies to the ingredients require postponement. Because the Sunshine Coast lifestyle often involves beach activities, outdoor sports, and sun exposure, timing your treatment series during cooler months (April through September) can make aftercare easier. That said, the treatment works year-round if you’re committed to strict sun protection and can avoid direct UV exposure during your treatment period.
If your primary concerns are deep static wrinkles, significant volume loss, or muscle-related lines, other treatments may deliver more noticeable results.
During your consultation, we’ll assess your skin and discuss whether Rejuran alone will achieve your goals or whether combining it with other approaches makes more sense for your specific concerns.